We’ll begin with Wikipedia’s explanation:

A ganglion cyst, also known as a bible cyst, is a swelling that often appears on or around joints and tendons in the hand or foot. The size of the cyst can vary over time. It is most frequently located around the dorsum of wrist and on the fingers. The term “Bible bump” comes from a common urban legend that treatment in the past consisted of hitting the cyst with a Bible or another large book.

The glamorous Manhattanite bibliophile Cynthia developed a small bible bump at the recent Baltimore Antiques Show. She came to our booth to complain of it, and a solution was proposed. Because I was not present, I will allow Mr. Ian Kahn of Lux Mentis to explain (video to follow):

Our friend Cynthia had a Ganglion Cyst on her wrist. As it was discussed by people at the Baltimore Antique and Book Fair, the home remedy of “whacking it with a heavy book” was proposed (the process is sometimes called a “bible bump“). While there were no bibles kicking about, there was a first edition copy of A. Rand’s, Atlas Shrugged (this the copy that has been previously mentioned for its obvious feline review (i.e. cat vomit staining to the front board)). The following video shows the proper and successful use of Atlas Shrugged in a medical procedure (Sunday Steinkirchner and Judith Dixon assisted).

Thanks to Josh of B&B Books for the video.